# Novel 2019 coronavirus genome

**URL:** <https://virological.org/t/novel-2019-coronavirus-genome/319>\
**Category:** SARS-CoV-2 coronavirus\
**Created:** [January 11, 2020, 1:05am UTC](https://virological.org/t/novel-2019-coronavirus-genome/319 "2020-01-11T01:05:32Z")\
**Posts on this page:** 1\
**Showing post:** 6

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**Author:** ![arambaut](https://virological.org/user_avatar/virological.org/arambaut/32/425_2.png) [@arambaut](https://virological.org/u/arambaut)\
**Post date:** [January 14, 2020, 12:02pm UTC](https://virological.org/t/novel-2019-coronavirus-genome/319/6 "2020-01-14T12:02:02Z")

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`IVDC-HB-01/2019` has been cell cultured with one round of passaging. This should be considered the most reliable. It may could have cell adaptations but it is identical to `WIV04/2019` which is direct sequenced so if independent, suggests there are no cell adaptations.

The first genome `WH-Human_1` has one SNP difference from all the others which may mean it is real. However it is not known if this genome is from a sample from one of the same patients as the other 5.

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